RBC compatibility
- Blood group AB individuals have both A and B antigens on the
surface of their RBCs, and their blood serum does not contain any
antibodies against either A or B antigen. Therefore, an individual
with type AB blood can receive blood from any group (with AB being
preferable), but can only donate blood to another group AB individual.
- Blood group A individuals have the A antigen on the surface
of their RBCs, and blood serum containing lgM antibodies
against the B antigen. Therefore, a group A individual can only
receive blood from individuals of groups A or O (with A being
preferable), and can donate blood to individuals of groups A or AB.
- Blood group B individuals have the B antigen on their surface
of their RBCs, and blood serum containing lgM antibodies against
the A antigen. Therefore, a group B individual can only receive blood
from individuals of groups B or O (with B being preferable), and can
donate blood to individuals of groups B or AB.
- Blood group O (or blood group zero in some countries)
individuals do not have either A or B antigens on the surface of their
RBCs, but their blood serum contains lgM anti-A antibodies and
anti-B antibodies against the A and B blood group antigens. Therefore,
a group O individual can only receive blood from a group O individual,
but they can donate blood to individuals of any ABO blood group (ie A,
B, O or AB). If a blood transfusion is needed in a dire emergency and
the time taken to process the recipients blood would cause a
detrimental delay, O Neg blood is issued
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